Table 1.
Clinical and demographic characteristics of melancholic adolescents with major depressive disorder (MDD), non-melancholic adolescents with MDD, and healthy controls
| Characteristic | Melancholic MDD n = 20 | Non-melancholic MDD n = 30 | Healthy controls n = 22 |
|---|---|---|---|
| Age (years) | 16.3 ± 2.1 | 15.6 ± 2.0 | 16.0 ± 2.7 |
| Gender (female/male) | 11/9 1(55/45%) | 16/14 1(53/47%) | 13/9 1(59/41%) |
| Ethnicity (Caucasian/African American/Hispanic/Asian/Other) | 9/6/1/3/1 1(45/30/5/15/5%) | 17/0/11/2/0 1(57/0/37/7/0%) | 13/2/1/4/2 1(59/9/5/18/9%) |
| Illness history | |||
| Duration of Illness (months) | 25.3 ± 22.1 2(3–84) | 14.9 ± 10.8 2(1.5–36) | 0 |
| History of suicide attempts | .9 ± 1.0 2(0–3) | .4 ± .7 2(0–3) | 0 |
| Medication-naïve/Medication-free/Medicated | 11/3/6 1(55/15/30%) | 17/2/11 1(57/7/37%) | 0 |
| 3 CDRS-R | 66.5 ± 14.7 2(42–97) | 50.4 ± 9.0 2(36–75) | 18.3 ± 2.5 2(16–27) |
| 4 BDI-II | 24.3 ± 11.9 2(10–53) | 21.0 ± 9.3 2(4–42) | 1.9 ± 2.7 2(0–11) |
| Current comorbidity | |||
| 5 ADHD | 0 | 3 1(10%) | 0 |
| Any anxiety disorder | 4 1(20%) | 11 1(37%) | 0 |
| Any comorbidity | 4 1(20%) | 12 1(40%) | 0 |
1
Respective percentages (may not add up to 100% due to rounding);
2
Range;
3
Children’s Depression Rating Scale-Revised;
4
Beck Depression Inventory, 2nd edn;
5
Attention deficit hyperactivity disorder.