. Author manuscript; available in PMC: 2014 Mar 1.

Published in final edited form as: Eur J Cancer Care (Engl). 2012 Dec 18;22(2):10.1111/ecc.12028. doi: 10.1111/ecc.12028

Table 3.

Total sample: longitudinal comparison of patients with distant metastasis to local/regional metastasis at intake, 5 and 11 weeks: LS means adjusted for age, number of comorbid conditions, type of treatment and time since cancer diagnosis

	Distant metastasis		Local/regional metastasis
Outcome	LS means	SE	LS means	SE	P-value
Physical functioning	55.8905	2.2104	65.4952	3.0910	0.0041^**
CES-D	13.8382	0.7839	13.7540	1.0925	0.9430
Anxiety	36.7698	0.9140	37.3993	1.2748	0.6466
Pain (BPI)	3.7527	0.2267	2.6102	0.3158	0.0009^**
Fatigue (BFI)	5.3299	0.2097	4.9785	0.2920	0.2652
Shortness of breath (FACT-B item)	3.0018	0.0851	3.2046	0.1186	0.1129
Nausea (FACT-B item)	3.4052	0.0702	3.4445	0.0976	0.7092
Sleep (FACT-B item)	2.3246	0.0895	2.3118	0.1249	0.9245
LTQL spiritual subscale	10.4960	0.5561	10.8035	0.7773	0.7129

^**

P < 0.01.

LS, least square; CES-D, Center for Epidemiologic Studies Depression Scale; BPI, Brief Pain Inventory; BFI, Brief Fatigue Inventory; FACT-B, Functional Assessment of Cancer Therapy-Breast Scale-Version 4; LTQL, Long-Term Quality of Life Instrument.