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Prolonged deficit in reversal learning induced by PCP. Withdrawal from subchronic PCP treatment led to an increased number of search errors in the reversal learning paradigm, which persisted for 4 weeks. Saline-Saline group was treated with saline twice daily for 6 weeks. PCP-Saline group was treated with PCP twice daily for 2 weeks, followed by saline twice daily for 1, 2, 3, or 4 weeks. *Significant increase compared with respective saline controls (n=8 per group).
