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IC50 of the top eight hits from libraries 7 and 8 against LYP.
| Cmpd # | Structure | IC50 (µM) |
|---|---|---|
| 7a |  |
0.30 ± 0.009 |
| 8a |  |
0.171 ± 0.004 |
| 8b |  |
0.259 ± 0.007 |
| 8c |  |
0.263 ± 0.006 |
| 8d |  |
0.31 ± 0.008 |
| 8e |  |
0.55 ± 0.03 |
| 8f |  |
0.259 ± 0.008 |
| 8g |  |
0.67 ± 0.03 |
