Table 1.
qMT and DTI parameters
| Control mice (mean ± SD) |
Shiverer mice (mean ± SD) |
p-value | |||
|---|---|---|---|---|---|
| QMT | Pool size ratio | White matter | 0.099 ± 0.011 | 0.076 ± 0.008 | 0.002 |
| Gray matter | 0.071 ± 0.005 | 0.076 ± 0.007 | 0.14 | ||
| Fast rate (s−1) | White matter | 27 ± 4 | 29 ± 8 | 0.58 | |
| Gray matter | 29 ± 8 | 28 ± 6 | 0.98 | ||
| Slow rate (s−1) | White matter | 1.10 ± 0.03 | 1.02 ± 0.02 | 0.0002 | |
| Gray matter | 1.05 ± 0.04 | 1.07 ± 0.05 | 0.52 | ||
| DTI | Radial diffusivity (µm2/ms) | White matter | 0.09 ± 0.01 | 0.12 ± 0.02 | 0.01 |
| Gray matter | 0.23 ± 0.01 | 0.24 ± 0.02 | 0.78 | ||
| Axial diffusivity (µm2/ms) | White matter | 0.40 ± 0.03 | 0.42 ± 0.04 | 0.27 | |
| Gray matter | 0.31 ± 0.02 | 0.31 ± 0.03 | 0.91 |
The p-value represents the statistically significant difference calculated by t-test.