Figure 2.

The dominant cellular infiltrate in the conjunctival epithelium in SJS-TEN is characterized by an increase in CD45^INTCD11b⁺CD16⁺CD14⁻ neutrophils. Twenty-one healthy subjects were compared with 10 patients with SJS-TEN (six patients in the acute stages, open square; and 4 in the chronic stages of systemic disease, closed square). Representative flow cytometry plots are shown. Statistical comparisons between healthy and SJS-TEN conjunctival leukocytes and lymphocytes (A), CD45⁺CD3⁺CD56⁻CD8αβ⁺ T cells ([B], boxed); CD45^INTCD11b⁺CD16⁺CD14⁻ neutrophil (C); and CD45⁺CD14⁺CD16⁻ monocyte (D) populations were undertaken by the Mann-Whitney U test. NS, not significant. *P > 0.05. **P < 0.01).