The dominant cellular infiltrate in the conjunctival epithelium in SJS-TEN is characterized by an increase in CD45INTCD11b+CD16+CD14− neutrophils. Twenty-one healthy subjects were compared with 10 patients with SJS-TEN (six patients in the acute stages, open square; and 4 in the chronic stages of systemic disease, closed square). Representative flow cytometry plots are shown. Statistical comparisons between healthy and SJS-TEN conjunctival leukocytes and lymphocytes (A), CD45+CD3+CD56−CD8αβ+ T cells ([B], boxed); CD45INTCD11b+CD16+CD14− neutrophil (C); and CD45+CD14+CD16− monocyte (D) populations were undertaken by the Mann-Whitney U test. NS, not significant. *P > 0.05. **P < 0.01).