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. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: J Invest Dermatol. 2012 Nov 29;133(5):1188–1196. doi: 10.1038/jid.2012.403

Table 3.

NMSC recurrence rates five years after different treatments, in subgroups of tumors conventionally believed to be high-risk for recurrence

Tumors at High Risk for Recurrence 5 year recurrence rates [95% CI]
University site VA site
No. Destruction Excision Mohs surgery No. Destruction Excision Mohs surgery
Squamous cell carcinoma 189 4.9% [0, 11.4] 6.1% [0, 12.5] 0% [0, 4.0] 177 0% [0, 8.5] 3.1% [0, 6.5] 4% [0, 11.4]
Diameter ≥ 20 mm 211 15.4% [1.9, 27.0] 0% [0, 7.4] 1.6% [0, 4.6] 198 0% [0, 16.1] 3.7% [0, 7.3] 0% [0, 10.3]
Invasive histologically 577 5.1% [0, 10.5] 1.4% [0, 3.2] 2.2% [0.3, 4.1] 3 499 4.6% [0, 9.7] 3.6% [1.1, 6.1] 1.8% [0, 4.3]
Located in H-zone of face(Swanson etal., 1983) 269 9.5% [0, 25.6] 6.3% [0, 14.5] 1.2% [0, 2.8] 2 275 0% [0.0, 19.5] 5.8% [0.7, 10.7] 3% [0, 6.3]
High-risk location and size(NCCN, 2011)' 1 185 0% [0.0, 41.0] 7.0% [0, 15.9] 0% [0.0, 3.4] 175 0% [0, 36.9] 4.8% [0, 10.0] 3.2% [0, 7.5]
1

Tumor located in H-zone of face or hand or genitals; size >=6 mm

2

P=0.05

3

P=0.04