Table 1.
BMI-1 Score | ||||||
---|---|---|---|---|---|---|
BMI-1-low | BMI-1-high | |||||
All Patients | Negative | 1+ | 2+ | 3+ | p-value* | |
Total Number | 130 | 18 | 6 | 33 | 73 | |
(%) | (100) | (13.8) | (4.6) | (25.4) | (56.2) | |
Median age, years (range) | 13 (0, 47) | 13 (5, 47) | 15 (6, 31) | 15 (0, 30) | 13 (0, 46) | 0.76(1) |
Gender | ||||||
Male (%) | 84 (65) | 13 | 1 | 25 | 45 | 0.04(2); 0.49(3) |
Female (%) | 46 (35) | 5 | 5 | 8 | 28 | |
Stage | ||||||
Localized (%) | 99 (85) | 11 | 4 | 22 | 62 | 0.43(2) |
Metastatic (%) | 18 (15) | 4 | 1 | 4 | 9 | |
Unknown | 13 | 3 | 1 | 7 | 2 | |
Region | ||||||
Pelvis (%) | 20 (15) | 4 | 1 | 3 | 12 | 0.56(2) |
Non-Pelvis (%) | 110 (85) | 14 | 5 | 30 | 61 | |
Tissue of Origin | ||||||
Bone | 75 | 12 | 3 | 19 | 41 | 0.72(2) |
Soft Tissue | 50 | 5 | 2 | 11 | 32 | |
Unknown | 5 | 1 | 1 | 3 | 0 | |
Chemotherapy status | ||||||
Pre-Chemotherapy | 99 | 13 | 3 | 24 | 59 | 0.49(2) |
Post-chemotherapy | 15 | 3 | 1 | 4 | 7 | |
Unknown | 16 | 2 | 2 | 5 | 7 | |
Translocation status | ||||||
EWS-ETS Fusion + | 70 | 5 | 5 | 18 | 42 | 0.13(2) |
No fusion detected | 5 | 2 | 0 | 0 | 3 | |
Unknown | 55 | 11 | 1 | 15 | 28 | |
p16 genomic status known (N=24) | ||||||
Wild type | 22 | 3 | 2 | 7 | 10 | 0.52(2) |
Deleted | 2 | 0 | 1 | 0 | 1 | |
p53 mutation status known (N=24) | ||||||
Wild type | 16 | 3 | 1 | 5 | 7 | 0.55(2) |
Mutant | 8 | 0 | 2 | 2 | 4 |
p-value from analysis of variance1, 4×2 Fisher’s exact test (unknowns excluded) 2, 2×2 Fisher’s exact test3