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. Author manuscript; available in PMC: 2013 Jul 15.
Published in final edited form as: Clin Cancer Res. 2010 Nov 3;17(1):56–66. doi: 10.1158/1078-0432.CCR-10-1417

Table 1.

Clinical and Molecular Features of Primary ESFT Biopsies

BMI-1 Score
BMI-1-low BMI-1-high
All Patients Negative 1+ 2+ 3+ p-value*
Total Number 130 18 6 33 73
(%) (100) (13.8) (4.6) (25.4) (56.2)
Median age, years (range) 13 (0, 47) 13 (5, 47) 15 (6, 31) 15 (0, 30) 13 (0, 46) 0.76(1)
Gender
 Male (%) 84 (65) 13 1 25 45 0.04(2); 0.49(3)
 Female (%) 46 (35) 5 5 8 28
Stage
 Localized (%) 99 (85) 11 4 22 62 0.43(2)
 Metastatic (%) 18 (15) 4 1 4 9
 Unknown 13 3 1 7 2
Region
 Pelvis (%) 20 (15) 4 1 3 12 0.56(2)
 Non-Pelvis (%) 110 (85) 14 5 30 61
Tissue of Origin
 Bone 75 12 3 19 41 0.72(2)
 Soft Tissue 50 5 2 11 32
 Unknown 5 1 1 3 0
Chemotherapy status
 Pre-Chemotherapy 99 13 3 24 59 0.49(2)
 Post-chemotherapy 15 3 1 4 7
 Unknown 16 2 2 5 7
Translocation status
 EWS-ETS Fusion + 70 5 5 18 42 0.13(2)
 No fusion detected 5 2 0 0 3
 Unknown 55 11 1 15 28
p16 genomic status known (N=24)
 Wild type 22 3 2 7 10 0.52(2)
 Deleted 2 0 1 0 1
p53 mutation status known (N=24)
 Wild type 16 3 1 5 7 0.55(2)
 Mutant 8 0 2 2 4
*

p-value from analysis of variance1, 4×2 Fisher’s exact test (unknowns excluded) 2, 2×2 Fisher’s exact test3