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. Author manuscript; available in PMC: 2013 Jul 15.
Published in final edited form as: Arch Neurol. 2011 Jun;68(6):814–821. doi: 10.1001/archneurol.2011.110

Table 3.

Pathological changes in pmp22−/− spinal roots.

Mouse No Age Sex Slide No Root Axonal Swelling Amyelinated axons
1 4m F 18 VR 2+ 2+
19 VR 2+ 2+
16 VR 2+ 2+
15 VR 0 3+
17 VR 1+ 3+

11 DR 2+ 2+
8 DR 2+ 1+
7 DR 2+ 1+
9 DR 2+ 1+
10 DR 2+ 0

2 4m F D5 VR 2+ 3+
C4 VR 1+ 3+
C5 VR 1+ 3+
D2 VR 3+ 2+
C3 VR 2+ 3+

B2 DR 1+ 0
B3 DR 2+ 1+
B6 DR 2+ 1+

3 2.5m F C6 VR 2+ 3+
D2 VR 1+ 1+
D5 VR 1+ 1+

33 DR 1+ 0
B5 DR 1+ 0
B2 DR 2+ 0
B1 DR 2+ 0
A6 DR 2+ 0

m=months VR = Ventral roots DR = Dorsal roots

0 = none of the pathological change; 1+ = The pathological change was in <5 myelinated fibers; 2+ = The pathological change was in >5 fibers and readily detectable in all examined fields; 3+ = The pathological change were numerous in any examined field.