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. 2013 Mar 6;33(10):4216–4233. doi: 10.1523/JNEUROSCI.3441-12.2013

Figure 6.

Figure 6.

Iba1+ microglia phagocytose neural precursor cells in the developing neocortex. A–D, Iba1+ microglia (green) in the E80 macaque SVZ contact and envelope Tbr2+ neural precursor cells (red). E, An Iba1+ microglial cell (green) enveloping a PCNA-positive mitotic cell (red). F, A Tbr2+ nucleus (red, white arrowhead) inside an Iba1+ microglial cell (green). The nucleus of the microglial cell (DAPI, blue) is indicated by a white arrow. G, H, Microglia (green) contained Tbr2+ (red) puncta indicating degradation after phagocytosis. I, J, Microglia (green) contact and envelope Pax6+ precursor cells (red). Panels show confocal optical plane images. Nuclei stained with DAPI (blue). Scale bar: (in A) A–J, 10 μm.