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Doxycycline inhibits MMP activity during contraction. The total MMP activity released in the medium by F10 and F11 cells with/without doxycycline treatment was measured at day 0, 3, and 7 during contraction using a FRET-based assay. MMP activity is expressed as fluorescence levels (mean ± SEM; F10, n = 3; F11, n = 2).
