Table.

Quantitative RT-PCR C_T Values for MMP mRNA Expression Levels During Gel Contraction

Gene	MMP1		MMP2		MMP7		MMP9		MMP12		HPRT1
Dox	–	+	–	+	–	+	–	+	–	+	–	+
F10
Day 0	31.1 ± 0.4	29.1 ± 2.1	25.1 ± 0.5	24.5 ± 0.6	39.6 ± 0.3	38.2 ± 0.9	39.0 ± 0.3	37.5 ± 1.0	34.8 ± 0.8	34.1 ± 0.8	29.8 ± 0.8	29.8 ± 0.8
Day 3	23.3 ± 0.7	24.0 ± 0.5	23.4 ± 0.4	22.8 ± 0.2	35.9 ± 0.4	36.7 ± 0.7	33.9 ± 0.5	34.0 ± 0.7	31.7 ± 0.8	32.9 ± 0.7	30.9 ± 0.8	30.4 ± 0.5
Day 7	23.0 ± 0.4	25.9 ± 0.7	22.1 ± 0.2	22.2 ± 1.2	36.3 ± 0.2	37.2 ± 1.0	34.6 ± 0.5	35.5 ± 0.9	30.3 ± 0.8	32.7 ± 0.9	30.0 ± 0.7	30.1 ± 1.0
F11
Day 0	30.4 ± 0.4	29.4 ± 0.1	26.5 ± 2.3	27.7 ± 3.4	37.0 ± 0.1	n/a	40.4 ± 0.9	37.0 ± 2.6	34.4 ± 1.3	34.4 ± 1.0	31.9 ± 0.9	32.1 ± 0.8
Day 3	26.3 ± 0.2	27.0 ± 0.5	23.5 ± 0.2	21.9 ± 0.9	41.3 ± 1.4	39.2 ± 0.6	39.0 ± 0.2	39.7 ± 0.5	34.1 ± 1.7	37.0 ± 0.4	32.0 ± 0.4	30.3 ± 1.2
Day 7	25.6 ± 0.5	27.6 ± 0.7	23.2 ± 0.2	22.4 ± 1.3	40.8 ± 0.9	40.5 ± 0.7	39.9 ± 0.6	41.1 ± 1.3	33.6 ± 1.4	38.5 ± 0.6	32.0 ± 0.6	30.6 ± 1.6

C_T values are averaged from n ≥ 3 experiments.