Figure 7.
In the full model, including both GL and EPL circuitry, muscarinic activation improves MC spike synchronization. A, Current-clamp responses of two pairs of MCs under control conditions. B, As in A, but with mAChR neuromodulation active. C, Current-clamp responses of two pairs of GCs under control conditions. D, As in B, but with muscarinic cholinergic neuromodulation active. E, Time series of total GABAA-mediated synaptic chloride conductance received from all presynaptic GCs by three representative MCs under control conditions. F, As in E, but with muscarinic cholinergic neuromodulation active. Black vertical arrows indicate the onset of odor stimulation (same for Fig. 10).