Table 6.
Average odor-evoked MC firing rates (mean ± SD) and network oscillation frequencies in the default model, modified model 1, and modified model 2 under four different neuromodulatory states
| Control | nAChR | mAChR | nAChR + mAChR | |
|---|---|---|---|---|
| MC firing rate (Hz) | ||||
| Default model | 6.7 ± 4.9 | 6.3 ± 6.7 | 5.5 ± 4.5 | 5.4 ± 6.2 |
| Modified model 1 | 12.1 ± 9.4 | 11.8 ± 11.7 | 9.2 ± 8.9 | 9.4 ± 10.6 |
| Modified model 2 | 19.5 ± 10.7 | 17.8 ± 13.4 | 18.8 ± 10.5 | 16.5 ± 13.7 |
| Oscillation frequency (Hz) | ||||
| Default model | 33.0 | 30.0 | 30.5 | 31.1 |
| Modified model 1 | 33.0 | 31.7 | 32.4 | 33.0 |
| Modified model 2 | 37.9 | 40.9 | 41.5 | 40.9 |
In modified model 1, the PGC→MC synaptic weight was reduced from 8 to 5, and the GC→MC synaptic weight was increased from 1 to 2. Modified model 2 shares the parameters of modified model 1, except that the GABAA decay time constant of the GC→MC synapses was reduced from 18 ms to 3 ms.