Figure 1.

CORT exposure destabilizes CA1 dendritic structure. a, Representative CA1 neurons in control, CORT, and washout groups. b, CORT reduced dendritic branching in basal, but not apical, trees, and branch points failed to normalize with a washout period. c, Total dendritic length was also diminished in mice with a history of CORT exposure. d, e, Sholl analyses revealed no effects on apical dendritic arborization (d), but basal arbors 75–125 μm from the cell body simplified after CORT, and they failed to recover with a 1-week washout period (e). Symbols/bars, means ± SEM, *p < 0.05.