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. Author manuscript; available in PMC: 2013 Jul 15.
Published in final edited form as: Nature. 2012 Jun 13;486(7402):271–275. doi: 10.1038/nature11090

Figure 3. Expression of the mgtC coding region inside macrophages is dependent on its leader region's ability to sense ATP, a property required for Salmonella virulence.

Figure 3

d, Relative mRNA levels of the mgtC, mgtB and mgtA coding regions of wild-type Salmonella harboring the wild-type mgtCBR leader (14028s) inside J774 A.1 macrophages at the indicated times after infection. e, Same as in (d) except using a mutant Salmonella with the chromosomal A nucleotides at position 44-46 of the mgtCBR leader substituted by Ts (EL341). f, Survival of C3H/HeN mice inoculated intraperitoneally with ~104 colony forming units of wild-type Salmonella (14028s) or ATP-sensing defective mutant (EL341) or deleted for both the mgtC and mgtB coding regions (EL6).