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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Eur J Neurosci. 2012 Oct 8;37(2):242–250. doi: 10.1111/ejn.12010

Fig. 3.

Fig. 3

Chronic stress leads to a decrease in mPer1 and mPer2 expression in the NAc. WT mice were subjected to 10 days of social defeat stress followed by 28 days of vehicle (veh) (n = 8) or fluoxetine (n = 6) treatment (pellets implanted s.c.). Control mice were only subjected to the 28 days of vehicle (n = 7) or fluoxetine pellets (n = 6), but no stress. mPer1 and mPer2 mRNA expression was significantly decreased in the NAc following chronic stress (*p<0.05) (A and B). Fluoxetine treatment following social defeat stress resulted in expression levels that were not different from control animals.