Table 10.
Summary of multiple logistic regression models for outcome for Bedside and WHO models
| Covariate | OR | 95% CI | P value | AUROCC 95% CI | |
|---|---|---|---|---|---|
|
Bedside |
|
|
|
|
0.93 (0.90-0.96) |
| Anaemia |
2.510 |
1.173 |
5.373 |
0.018 |
|
| Jaundice |
3.235 |
1.534 |
6.823 |
0.002 |
|
| Temperature 0C |
0.673 |
0.490 |
0.926 |
0.015 |
|
| Pulse/min |
1.031 |
1.007 |
1.056 |
0.010 |
|
| Respiratory rate/min |
1.061 |
1.010 |
1.115 |
0.018 |
|
| GCS |
0.717 |
0.654 |
0.785 |
<0.001 |
|
| Treatment with ACT |
0.387 |
0.134 |
1.118 |
0.080 |
|
|
Bedside + Simple Lab |
0.96 (0.93 -0.98) |
||||
| Temperature 0C |
0.579 |
0.405 |
0.829 |
0.003 |
|
| Respiratory rate/min |
1.081 |
1.027 |
1.139 |
0.003 |
|
| Log10 parasitaemia |
8.606 |
3.525 |
21.011 |
<0.001 |
|
| GCS |
0.663 |
0.589 |
0.745 |
<0.001 |
|
| % Trophozoites and schizonts |
1.029 |
1.014 |
1.045 |
<0.001 |
|
| Treatment with ACT |
0.253 |
0.078 |
0.825 |
0.023 |
|
|
WHO (1990) |
0.95 (0.90-1.00) |
||||
| GCS |
0.673 |
0.590 |
0.767 |
<0.001 |
|
| Serum creatinine μmol/L |
1.005 |
1.001 |
1.009 |
0.007 |
|
| Serum bicarbonate mmol/L |
0.844 |
0.763 |
0.934 |
0.001 |
|
| Serum total bilirubin μmol/L |
1.006 |
1.001 |
1.010 |
0.011 |
|
| Log10 parasitaemia |
1.902 |
1.060 |
3.410 |
0.031 |
|
| Treatment with ACT |
0.838 |
0.224 |
3.142 |
0.794 |
|
|
WHO (2000) and Adapted AQ a |
0.97 (0.96-0.99) |
||||
| GCS |
0.673 |
0.582 |
0.778 |
<0.001 |
|
| Serum bicarbonate mmol/L |
0.856 |
0.747 |
0.980 |
0.024 |
|
| Serum lactate mmol/L |
1.197 |
1.052 |
1.362 |
0.006 |
|
| Log10 parasitaemia |
2.460 |
1.168 |
5.182 |
0.018 |
|
| Serum creatinine μmol/L |
1.006 |
1.002 |
1.010 |
0.003 |
|
| Treatment with ACT | 1.000 | 0.220 | 4.555 | 1.000 | |
All estimates are adjusted for treatment with ACT and study site. a the same variables were identified from the WHO (2000) and Adapted AQ models.