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IC50 values for PBD peptides derived from CDC25c and PBIP
| SCCP ID | Sequence | PLK1 PBD IC50 |
|---|---|---|
| 292 | LLCS[pT]PNGL | 0.42 |
| 5821 | Ac-LLCS[pT]PNGL | 0.5 |
| 345 | LLCSEPNGL | 350 |
| 5795 | LDCS[pT]PNGL | 3 |
| 5783 | LLAAAPNGL | >600 |
| 5714 | S[pT]PNGL | >600 |
| 5649 | LHS[pT]AI | 200 |
| 5781 | Ac-LHS[pT]AI | 5 |
| 5782 | Ac-AHS[pT]AI | 15 |
| 5743 | Ac-PLHS[pT]A | 2 |
| 5744 | Ac-PLHSEA | 500 |
