SOCS-1, TNF-α, and SREBP-1 expression in liver tissue of placebo- and IDV-administered ZDF rats. Liver tissue homogenates were prepared from ZDF rats after placebo or IDV administration for 7 wk and processed for immunoblotting analyses of SOCS-1 (A), TNF-α (B), and SREBP-1 (C). A–C: quantified data; each bar is mean ± SE (n = 4 in each group) of the respective protein. Insets: representative immunoblots for each protein and corresponding GAPDH control. *P ≤ 0.05, significantly different from 5F group. #P ≤ 0.05, significantly different from 12F group.