Table 3. Multiple-adjusted analysis for OS and DSS among the whole population (n = 2433).

Variables	OS			DSS
	HR	95% CI	P	HR	95% CI	P
Age, years			<0.001			<0.001
<46	Ref			Ref
≥46	1.83	1.58–2.12		1.65	1.40–1.96
Sex			<0.001			<0.001
Male	Ref			Ref
Female	0.68	0.57–0.82		0.69	0.56–0.86
UICC T Stage			<0.001			<0.001
T1–T2	Ref			Ref
T3–T4	1.35	1.17–1.57		1.34	1.13–1.59
UICC N Stage			<0.001			<0.001
N0–N1	Ref			Ref
N2–N3	1.44	1.23–1.67		1.45	1.21–1.74
Treatment			0.049			0.064
RT	Ref			Ref
RT+CT	1.18	1.00–1.38		1.23	1.02–1.49
BMI+Weight loss(2×3 groups)			<0.001†			<0.001†
NW+LWL	Ref			Ref
NW+HWL	1.45	1.18–1.78	<0.001	1.57	1.22–2.01	<0.001
UW+LWL	1.25	0.89–1.75	0.191	1.23	0.80–1.88	0.348
UW+HWL	2.56	1.65–3.56	<0.001	2.66	1.82–3.88	<0.001
OW+LWL	0.82	0.64–1.05	0.116	0.90	0.67–1.22	0.501
OW+HWL	0.98	0.79–1.22	0.881	1.08	0.83–1.40	0.577

Footnote: Ref, reference; HR, hazard ratio.

^†result of joint test.