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. Author manuscript; available in PMC: 2013 Jul 15.
Published in final edited form as: Nat Neurosci. 2012 Nov 25;16(1):79–88. doi: 10.1038/nn.3274

Figure 8.

Figure 8

Pairing under anesthesia improves perception. a, Detection; animal anesthetized with pentobarbital during pairing. Hits increased after pairing (before: 30.6±16.3%, after: 67.3±6.5%, p<0.04). False alarms were unchanged after pairing (before: 27.2±5.2%, after: 27.3±1.9%, p>0.4), increasing d’ from 0.4 to 0.8. . b, Narrowband; pentobarbital anesthesia during pairing. Hits increased (before: 39.0±2.7%, after: 63.5±7.9%, p<0.03), false alarms were unchanged (before: 20.9±2.9%, after: 22.4±3.5%, p>0.7), increasing d’ from 0.6 to 1.1. c, Wideband; pentobarbital anesthesia during pairing (hits before: 54.8±11.9%, after: 75.1±1.1%, p>0.1; false alarms before: 6.8±1.7%, after: 4.3±2.0%, p>0.3; d’ before: 1.7, after: 1.8). d, Summary of experiments with pentobarbital anesthesia during and 1-3 hours post-pairing. Performance on wideband (triangles), narrowband (inverted triangles), and detection (squares) tasks was assessed 30-60 minutes pre-pairing and 1-2 hours after recovery. Performance improved on detection (d’ before: 0.9±0.1, after: 1.3±0.2, N=7, p<0.03) and narrowband recognition (d’ before: 0.4±0.1, after: 0.7±0.2, N=5, p<0.02), but not wideband (d’ before: 1.6±0.2, after: 2.0±0.4, N=5, p>0.05). e, Detection; animal anesthetized with isoflurane before pairing. Hits increased after pairing (before: 53.3±3.3%, after: 83.3±9.6%, p<0.03). False alarms were unchanged (before: 15.1±2.6%, after: 20.7±4.0%, p>0.1), increasing d’ from 0.8 to 1.4. f, Narrowband recognition; animal anesthetized with isoflurane during pairing. Hits increased (before: 36.8±5.5%, after: 62.1±9.4%, p<0.04), false alarms were unchanged (before: 30.6±3.6%, after: 36.1±4.2%, p>0.1), increasing d’ from 0.2 to 0.7. g, Wideband recognition; animal anesthetized with isoflurane during pairing. Behavior was unchanged (hits before: 69.4±12.3%, after: 74.7±5.4%, p>0.7; false alarms before: 9.2±1.9%, after: 11.9±2.2%, p>0.3; d’ before pairing: 1.8, after: 1.8). h, Summary of experiments with isoflurane anesthesia during pairing. Performance improved on detection (d’ before: 1.1±0.4, after: 1.7±0.5, N=6, p<0.04) and narrowband (d’ before: 0.2±0.2, after: 0.5±0.1, N=5, p<0.05), but not wideband (d’ before: 1.5±0.2, after: 1.9±0.1, N=3, p>0.1). Error bars show s.e.m.