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. 2013 Jul 13;6:269. doi: 10.1186/1756-0500-6-269

Table 4.

Clinical outcomes 0-48 months

Outcome (range) Age years N 0 months
48 months
0-48 month difference*
SRM
Mean (95%-CI) Mean (95%-CI) Mean (95%-CI) P-value
All diagnoses
Symptom Score (0-10)
-All patients
1-75
1501
6.09 (6.00-6.18)
3.26 (3.14-3.37)
2.83 (2.71-2.96)
<0.001
1.13
-Adults
17-75
1067
6.07 (5.96-6.17)
3.41 (3.27-3.54)
2.66 (2.51-2.81)
<0.001
1.09
-Children
1-16
434
6.15 (5.98-6.32)
2.90 (2.68-3.11)
3.25 (3.01-3.50)
<0.001
1.25
-Art therapy
1-75
273
6.19 (6.00-6.38)
3.24 (2.98-3.50)
2.95 (2.68-3.23)
<0.001
1.28
-Eurythmy therapy
1-75
791
6.23 (6.10-6.36)
3.35 (3.18-3.51)
2.88 (2.70-3.06)
<0.001
1.12
-Rhythmical massage Therapy
1-75
146
6.06 (5.78-6.33)
3.56 (3.16-3.96)
2.50 (2.08-2.91)
<0.001
0.98
-Medical therapy
1-75
291
5.63 (5.43-5.84)
2.88 (2.62-3.14)
2.75 (2.47-3.04)
<0.001
1.12
First ranked symptom (0-10)
1-75
1491
6.42 (6.32-6.52)
3.29 (3.29-3.42)
3.13 (2.99-3.28)
<0.001
1.09
CES-D (0-60)
17-75
849
21.83 (21.02-22.64)
15.34 (14.55-16.13)
6.49 (5.72-7.27)
<0.001
0.56
SF-36 Physical Component
17-75
1043
42.98 (42.33-43.68)
46.67 (46.01-47.33)
3.69 (3.11-4.27)
<0.001
0.39
SF-36 Mental Component
17-75
1043
37.90 (37.14-38.66)
45.41 (44.69-46.13)
7.51 (6.75-8.26)
<0.001
0.60
SF-36 scales (0-100)
-Physical Function
17-75
1069
74.70 (73.28-76.13)
80.30 (78.84-81.76)
5.60 (4.38-6.82)
<0.001
0.28
-Role Physical
17-75
1063
44.75 (42.38-47.12)
66.35 (63.95-68.74)
21.60 (19.03-24.17)
<0.001
0.51
-Role Emotional
17-75
1059
49.32 (46.79-51.86)
70.46 (68.08-72.84)
21.14 (18.44-23.84)
<0.001
0.47
-Social Functioning
17-75
1072
59.17 (57.57-60.76)
74.95 (73.43-76.47)
15.79 (14.12-17.46)
<0.001
0.57
-Mental Health
17-75
1070
53.62 (52.44-54.80)
65.32 (64.12-66.52)
11.70 (10.54-12.86)
<0.001
0.60
-Bodily Pain
17-75
1070
54.19 (52.47-55.91)
67.70 (66.01-69.38)
13.51 (11.84-15.17)
<0.001
0.49
-Vitality
17-75
1070
38.05 (36.93-39.18)
51.72 (50.48-52.97)
13.67 (12.41-14.92)
<0.001
0.65
-General Health
17-75
1061
50.22 (49.04-51.39)
59.12 (57.80-60.45)
8.91 (7.76-10.06)
<0.001
0.47
Diagnosis groups
ADHD: FBB-HKS Total (0-3)
3-16
60
1.74 (1.61-1.87)
1.25 (1.08-1.41)
0.49 (0.34-0.64)
<0.001
0.85
Anxiety Severity (0-10)
17-75
61
7.08 (6.61-7.55)
3.72 (2.99-4.45)
3.36 (2.67-4.06)
<0.001
1.24
Asthma Severity (0-10)
2-70
88
5.50 (5.04-5.96)
3.11 (2.59-3.64)
2.39 (1.86-2.91)
<0.001
0.96
Migraine Severity (0-10)
17-75
44
6.77 (6.23-7.32)
4.18 (3.34-5.02)
2.59 (1.84-3.34)
<0.001
1.05
Depression: CES-D (0-60)
17-70
133
34.93 (33.58-36.27)
19.75 (17.58-21.92)
15.18 (12.94-17.41)
<0.001
1.16
Low back pain: HFAQ (0-100)
17-75
73
62.13 (57.54-66.72)
75.71 (71.48-79.95
13.59 (9.83-17.34)
<0.001
0.84
Low back pain: LBPRS (0-100) 17-75 72 36.61 (32.75-40.46) 27.69 (23.37-32.01) 8.92 (5.11-12.73) <0.001 0.55

Patients with available baseline values, last value carried forward. CI Confidence interval. *Positive differences indicate improvement. SRM Standardised Response Mean effect size (minimal: < 0.20, small: 0.20-0.49, medium: 0.50-0.79, large: ≥0.80). CES-D Center for Epidemiological Studies Depression Scale, German version [34,35], ADHD Attention Deficit Hyperactivity Symptoms, FBB-HKS Total Fremdbeurteilungsbogen für Hyperkinetische Störungen (parents’ questionnaire for ADHD core symptoms), Total score [53,54]), HFAQ Hanover Functional Ability Questionnaire [51], LBPRS Low Back Pain Rating Scale Pain Score [52].