Figure 2.
Differentiation of basal forebrain progenitors to cholinergic neurons and GABAergic interneurons. (a) Schematic of neuronal differentiation from basal forebrain progenitors. NE, neuroepithelia. (b) Quantification of the percentage of ChAT+ and GABA+ neurons in βIII-tubulin+ (βIII-T+) cells. Error bars, s.e.m. (c) Immunofluorescence images of ChAT+ cholinergic neurons immunostained for βIII-tubulin (βIII-T), VAChT, NKX2.1 and FOXG1. (d) Immunofluorescence images of GABA neurons immunostained for βIII-tubulin (βIII-T), NKX2.1 and GAD65. TO, topo3; HO, Hoechst staining. Scale bars, 50 μm.