Table 4.
Systolic and diastolic blood pressure adjusted-means* among men and women according to genotype [mean ± SD, (95% CI)]
| Men | Women | |||||
|---|---|---|---|---|---|---|
|
rs9939609 |
TT |
TA/AA |
P value |
TT |
TA/AA |
P value |
| (n = 30) |
(n = 56) |
(n = 45) |
(n = 86) |
|||
| Systolic BP (mmHg) |
153.7 ±20.7 |
150.8 ±20.9 |
0.6 |
155.9 ±21.5 |
150.8 ±20.4 |
0.2 |
| (146.1 – 161.3) |
(145.3 – 156.4) |
(149.6 – 162.2) |
(146.4 – 155.3) |
|||
| Diastolic BP (mmHg) |
89.9 ±12.5 |
87.7 ±12.7 |
0.5 |
87.5 ±12.7 |
87.2 ±12.1 |
0.9 |
| (85.4 – 94.4) |
(84.5 – 91.0) |
(83.7 – 91.2) |
(84.6 – 89.9) |
|||
| Mean BP (mmHg) |
111.1 ±13.7 |
108.8 ±13.5 |
0.5 |
110.6 ±13.7 |
108,2 ±13.7 |
0.5 |
| (106.2-116.0) |
(105.2-112.3) |
(106.5-114.7) |
(105,3-111,2) |
|||
|
rs17782313 |
TT |
TC/CC |
P value |
TT |
TC/CC |
P value |
| (n = 66) |
(n = 20) |
(n = 80) |
(n = 51) |
|||
| Systolic BP (mmHg) |
154.2 ±20.3 |
144.2 ±20.1 |
0.05 |
154.1 ±20.6 |
150.2 ±20.7 |
0.3 |
| (149.2 – 159.1) |
(135.3 – 153.2) |
(149.5 – 158.6) |
(144.3 – 155.9) |
|||
| Diastolic BP (mm Hg) |
90.1 ±12.2 |
83.2 ±12.1 |
0.03 |
87.5 ±12.5 |
86.9 ±12.9 |
0.8 |
| (87.2 – 92.9) |
(77.9 – 88.5) |
(84.8 – 90.2) |
(83.5 – 90.5) |
|||
| Mean BP (mmHg) | 111.3 ±13.5 (108.1-114.6) | 103.9 ±13.4 (98.0-109.8) | 0.02 | 109.8 ±13.4 (106.8-112.7) | 107.9 ±13.5 (104.1-111.7) | 0.5 |
* Means adjusted for age and BMI.