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. 2013 Jul 15;8(7):e69186. doi: 10.1371/journal.pone.0069186

Table 2. Postnatal and SHG diagnosis of OI.

Types Clinical Diagnosis SHG Diagnosis
Severity C. Fractures Stature Bone D. DI DDD SAAID GLCMEnergy Value (d = 7)
N High Negative Low (0.15)
I Mild No Normal Rarely Variable N.A. Negative Low (0.13)
II Severe Lethal Yes Severely Short Very Severe N.A. N.A. N.A. N.A.
III Severe Yes Very Short Moderate Severe Yes Low More Positive High (0.33)
IV Moderate Rarely Variable Short Mild Moderate Variable Low More Positive Medium (0.24)

N.: Normal, C. Fractures: Congenital Fractures, Bone D.: Bone Deformity, N.A.: Not Available, DI: Dentinogenesis Imperfecta, DDD: Depth-dependent decay, SAAID: SHG autofluorescence aging index of dermis, GLCM: Gray-level co-occurrence matrix, d: pixel distance.