Table 3.
Neuropsychological test scores and NPI-Q scores (mean (SD))
|
GADA |
Control |
p-values |
|
|---|---|---|---|
| (n = 21) | (n = 19) | ||
|
Global cognitive functioning | |||
| MMSE |
28.8 (1.7) |
29.1 (1.4) |
0.63 |
|
Intellectual ability (WAIS-III) | |||
| FIQ |
94.0 (16.2) |
105.8 (11.8) |
0.01 |
| VIQ |
96.0 (16.3) |
107.2 (13.9) |
0.03 |
| PIQ |
92.8 (16.2) |
100.5 (12.1) |
0.10 |
| VC |
97.6 (14.4) |
106.0 (13.9) |
0.07 |
| PO |
93.5 (14.4) |
102.5 (10.6) |
0.03 |
| WM |
93.6 (17.6) |
99.7 (11.6) |
0.20 |
| PS |
94.0 (16.0) |
96.5 (13.7) |
0.61 |
|
Attention | |||
| Digit Span, forward |
6.3 (1.3) |
6.8 (1.2) |
0.15 |
| Digit Span, backward |
5.0 (1.5) |
4.8 (1.0) |
0.78 |
| Stroop Test |
145.5 (82.0) |
112.4 (39.3) |
0.11 |
|
Memory | |||
| LMT, immediate |
23.8 (8.6) |
26.3 (7.8) |
0.34 |
| LMT, delay |
19.0 (7.7) |
23.0 (7.5) |
0.11 |
| RCFT, copy |
34.7 (2.7) |
35.5 (1.2) |
0.28 |
| RCFT, immediate |
19.1 (10.1) |
23.8 (5.2) |
0.07 |
| RCFT, delay |
18.5 (9.7) |
23.8 (4.8) |
0.03 |
| RCFT, recognition |
19.9 (2.1) |
20.6 (2.1) |
0.29 |
|
Executive functions | |||
| VF, phonemic (Fu/A/Ni) |
24.6 (7.3) |
31.3 (8.2) |
0.009 |
| VF, category (Animal) |
16.9 (4.1) |
17.6 (4.2) |
0.56 |
| TMT, part A |
49.4 (18.3) |
45.1 (15.1) |
0.43 |
| TMT, part B |
151.3 (122.0) |
108.6 (66.2) |
0.17 |
|
Neuropsychiatric state | |||
| NPI-Q severity† |
1.2 (2.0) |
0.4 (0.9) |
0.36 |
| NPI-Q distress† | 1.2 (2.5) | 0.2 (0.5) | 0.28 |
Higher scores indicate better performance on all of the neuropsychological tests except for the trail-making test and the Stroop test, in which higher scores indicate worse performance. High NPI-Q scores reflect worse neuropsychiatric status.
Abbreviations: GADA glutamic acid decarboxylase antibody, LMT logical memory test, RCFT Rey Osterrieth complex figure test, VF verbal fluency tests, TMT trail making test, NPI-Q neuropsychiatric inventory questionnaire.
† Mann-Whitney U test.