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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Cell Microbiol. 2013 Mar 22;15(8):1419–1426. doi: 10.1111/cmi.12127

FIG 3. SPF mice express significantly higher levels of CXCL2 in the junctional epithelium.

FIG 3

CXCL1 and CXCL2 immunohistochemical (IHC) staining of oral tissue. CXCL1 (A and B) and CXCL2 (C and D) expression was determined in GF (A and C) and SPF mice (B and D). Local structures are indicated as well as magnification with neutrophil staining detected in the junctional epithelium. The junctional epithelium appears detached from the tooth surface due to the fixing procedure. Lower panels represent a semi-quantitative analysis of CXCL1 (E) and CXCL2 (F) expression as described in the text: Y axes indicate the percentage of sections examined; X axes indicate staining intensity scores. ++, denotes statistically significant difference (Multi-level logistic regression test, N=120 tissue sections).