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. 2013 Jul 15;8(7):e68300. doi: 10.1371/journal.pone.0068300

Figure 1. The α5 subunit plays an importantrole in maintaining α4* nAChR levels.

Figure 1

(A and B) The α5-/-(α4 YFP) mice have significantly reduced α4YFP expression levels in the VTA compared with α5+/+(α4 YFP) quantified using western blot analysis. The values are expressed as mean α4 YFP expression (% of GAPDH) ± SEM (two-tailed unpaired t-test, * p=0.05). n=6-8 number of animals (two-tailed unpaired t-test, *p<0.05).