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. 2013 Jul 15;8(7):e69272. doi: 10.1371/journal.pone.0069272

Table 2. Summary of 23 case-control studies on exposure to electric and magnetic fields and breast cancer in females.

No 1st author, year of publication and country Cases Controls Exposure assessment method The matched factors between cases and controls Study period OR (95%CI) Scores
1 Vena JE(1991), USA 378 postmenopausal women in the Western New York Study of Breast Cancer 438 controls randomly selected from community Frequency and mode of use of electric blankets Age, region 1987–1989 0.89(0.67,1.19)
2 Loomis DP(1994), [15] USA 27882 Cases were female residents for 20 years and older at their death in 24 states. 110949 controls were random sample of women who died of any other underlying cause, excluding leukemia and brain cancer. Job title. Year of death, age, region 1985–1989 1.36(1.03,1.79) 6
3 Vena JE(1994), USA 290 premenopausal women who were admitted to hospitals in Niagara and Erie counties 289 controls who were residents of the same two counties, randomly selected from the New York State driver's license records Histories of electric blanket use Age, region 1986–1991 1.14(0.81,1.59) 5
4 Coogan PF(1996), USA 6888 cases were female residents of four states with incident breast cancer reported to four tumor registries 9529 controls were randomly selected from state driver's license lists and health care telephone number Job title Age, region 1988–1991 1.00(0.90,1.11) 7
5 Li C-Y(1997), Taiwan 1980 cases were residents of northern Taiwan reported to the National Cancer Registry of Taiwan 1880 controls were random selection of women with cancers excluded these cancers associated with magnetic field exposure Measurement and Estimation of magnetic fields in the residencies Age, sex, and date of diagnosis 1990–1992 1.10(0.93,1.31) 5
6 Coogan FP(1998) [12], USA 259 cases were permanent residents of five towns and reported to the Massachusetts Cancer Registry. 738 controls resided in the towns were selected by random digit dialing, lists of Medicare beneficiaries, and death certificates. Use of electric bed-warming devices and electric heat, Occupational history and residential history Age, region 1983–1986 0.99(0.74,1.33) 7
7 Gammon (1998), USA 1645 incident cases were residents of one of three US geographic areas with a tumor registry. 1498 controls were identified via random digit dialing Use of electric blankets Age, region 1990–1992 1.06(0.92,1.22) 6
8 Feychting M(1998) [13], Sweden 669 cases were identified through record linkage to the Swedish Cancer Registry. 669 controls were selected randomly among those who were included in the study base. The magnetic field at home were assessed through theoretical calculations Age, lived in the same parish, and lived near the same power line. 1960–1985 1.14(0.86,1.51) 6
9 Zheng (2000), USA 608 Cases either had breast-related surgery at the Yale-New Haven Hospital, or who were residents of Tolland County 609 controls had had breast-related surgery and who were histologically diagnosed with normal tissue or benign breast diseases. Use of electric blankets Age, region 1994–1997 0.86(0.69,1.09) 5
10 McElroy JA (2001) [21], USA 1,949 cases were identified from state wide tumor registries in Massachusetts, New Hampshire, and Wisconsin 2,498 cases were randomly selected from population lists as controls. Electric blanket and mattress cover use Age June 1994–July 1995 0.97(0.86,1.09) 6
11 Wijngaarden (2001), USA 843 cases were identified through the North Carolina Central Cancer Registry 773 Controls were sampled from lists of the Division of Motor Vehicles and Health Care Financing Administration Cumulative exposures to magnetic fields were based on a measurement survey. Age, race 1993–1995 0.94(0.76,1.16) 7
12 Davis S(2002),USA[23] 813 cases were identified by the Cancer Surveillance System of the Fred Hutchinson Cancer Research Center. 793 controls were resident and identified by random digit dialing. Measurements in the home and self-reported measures of at-home electric appliance use. Race, age and region November 1992–March 1995 0.99(0.77,1.28) 7
13 Kabat GC (2003a) [22],USA 1323 cases were identified from Health Care Financing Administration files was from the Long Island Breast Cancer Study Project (LIBCSP) 1362 controls were from the LIBCSP and controls were residents identified by random digit dialing and Health Care Financing Administration (HCFA) rosters. Electric blanket use Age, region August 1, 1996 to July 31, 1997. 1.11(0.94,1.30) 6
14 Kabat GC(2003b) [22],USA 666 cases was from the Electromagnetic Fields and Breast Cancer on Long Island Study (EBCLIS*) I 557 controls were from EBCLIS Electric blanket use Age, region, long-term residents August 1, 1996 to July 31, 1997. 0.97(0.76,1.23) 5
15 Schoenfeld ER (2003) [16], USA 576 cases was from the EBCLIS 585 controls were from EBCLIS In-home EMF measurements, wire mapping of overhead power lines Age, region, long-term residents August 1, 1996, to June 20, 1997. 1.03(0.82,1.30) 7
16 Kliukiene J (2003) [17],Norway 99 breast cancer cases from a cohort of Norwegian female radio and telegraph operators. 396 controls from the cohort alive at time of diagnosis. Calculated based on employment information. Magnetic field measurements Age, region January 1961 to the end of May 2002. 1.46(0.78,2.70) 6
17 Labreche F(2003)[19], Canada 608 cases were identified from records of pathology departments and cancer registries from hospitals. 667 controls had 32 different types of cancer from the same hospitals. Job Age, same hospital 1996–1997 1.22(0.93,1.61) 5
18 London SJ (2003) [24], USA 347 cases were identified by linkage to county and state tumor registries in Los Angeles County, California. 286 Controls were selected from a random sample of cohort members without breast cancer at baseline. Exposure was assessed by means of wiring configuration coding Race, age and region 1993–1999 1.26(0.87,1.83) 8
19 Zhu K, 2003(2003) [3], USA 304 cases lived in one of three Tennessee counties were identified through the Tennessee Cancer Reporting System. 305 controls were selected through random digit dialing. Electric blanket use Race, age and county 1995–1998 1.49(0.99,2.23) 6
20 Kliukiene J (2004) [17],Norway. 1830 cases of breast cancer were identified in a cohort of women living near a high-voltage power line in Norway. The 3658 controls were selected randomly from the cohort. Residential exposure by the lines, occupational exposure by job title, Magnetic field measurements for estimated time weighted average; Age, region 1986–1996 1.53(1.28,2.85) 9
21 Forssen (2000) UM[25], Sweden 440 cases living within 300 meters of transmission lines in the cohort were identified from the Swedish Cancer Registry. 439,One matched control per case at random was selected. Residential exposure by the power lines, and occupational exposure by job title, Age, region, type of house, power line 1960–1985 1.02(0.78,1.35) 8
22 Forssen UM(2005), Sweden 18365 cases were identified from the cancer registry gainfully 101973 controls were selected randomly from the study base. Job-exposure matrix based on personal magnetic field measurements Rgion 1976–1999 1.04(0.99,1.08) 6
23 McElroy JA (2007) [20],USA 6213 cases were identified through the North Carolina Central Cancer Registry. 7390 Controls were sampled from lists of the Division of Motor Vehicles and rosters of Medicare beneficiaries. Job title Age, region 1970–2002 1.06(0.99,1.14) 6

*:Women eligible for EBCLIS were those LIBCSP participants who had lived in their current residences for 15 years or more (long-term residents).