Table 2. Summary of 23 case-control studies on exposure to electric and magnetic fields and breast cancer in females.
No | 1st author, year of publication and country | Cases | Controls | Exposure assessment method | The matched factors between cases and controls | Study period | OR (95%CI) | Scores |
1 | Vena JE(1991), USA | 378 postmenopausal women in the Western New York Study of Breast Cancer | 438 controls randomly selected from community | Frequency and mode of use of electric blankets | Age, region | 1987–1989 | 0.89(0.67,1.19) | |
2 | Loomis DP(1994), [15] USA | 27882 Cases were female residents for 20 years and older at their death in 24 states. | 110949 controls were random sample of women who died of any other underlying cause, excluding leukemia and brain cancer. | Job title. | Year of death, age, region | 1985–1989 | 1.36(1.03,1.79) | 6 |
3 | Vena JE(1994), USA | 290 premenopausal women who were admitted to hospitals in Niagara and Erie counties | 289 controls who were residents of the same two counties, randomly selected from the New York State driver's license records | Histories of electric blanket use | Age, region | 1986–1991 | 1.14(0.81,1.59) | 5 |
4 | Coogan PF(1996), USA | 6888 cases were female residents of four states with incident breast cancer reported to four tumor registries | 9529 controls were randomly selected from state driver's license lists and health care telephone number | Job title | Age, region | 1988–1991 | 1.00(0.90,1.11) | 7 |
5 | Li C-Y(1997), Taiwan | 1980 cases were residents of northern Taiwan reported to the National Cancer Registry of Taiwan | 1880 controls were random selection of women with cancers excluded these cancers associated with magnetic field exposure | Measurement and Estimation of magnetic fields in the residencies | Age, sex, and date of diagnosis | 1990–1992 | 1.10(0.93,1.31) | 5 |
6 | Coogan FP(1998) [12], USA | 259 cases were permanent residents of five towns and reported to the Massachusetts Cancer Registry. | 738 controls resided in the towns were selected by random digit dialing, lists of Medicare beneficiaries, and death certificates. | Use of electric bed-warming devices and electric heat, Occupational history and residential history | Age, region | 1983–1986 | 0.99(0.74,1.33) | 7 |
7 | Gammon (1998), USA | 1645 incident cases were residents of one of three US geographic areas with a tumor registry. | 1498 controls were identified via random digit dialing | Use of electric blankets | Age, region | 1990–1992 | 1.06(0.92,1.22) | 6 |
8 | Feychting M(1998) [13], Sweden | 669 cases were identified through record linkage to the Swedish Cancer Registry. | 669 controls were selected randomly among those who were included in the study base. | The magnetic field at home were assessed through theoretical calculations | Age, lived in the same parish, and lived near the same power line. | 1960–1985 | 1.14(0.86,1.51) | 6 |
9 | Zheng (2000), USA | 608 Cases either had breast-related surgery at the Yale-New Haven Hospital, or who were residents of Tolland County | 609 controls had had breast-related surgery and who were histologically diagnosed with normal tissue or benign breast diseases. | Use of electric blankets | Age, region | 1994–1997 | 0.86(0.69,1.09) | 5 |
10 | McElroy JA (2001) [21], USA | 1,949 cases were identified from state wide tumor registries in Massachusetts, New Hampshire, and Wisconsin | 2,498 cases were randomly selected from population lists as controls. | Electric blanket and mattress cover use | Age | June 1994–July 1995 | 0.97(0.86,1.09) | 6 |
11 | Wijngaarden (2001), USA | 843 cases were identified through the North Carolina Central Cancer Registry | 773 Controls were sampled from lists of the Division of Motor Vehicles and Health Care Financing Administration | Cumulative exposures to magnetic fields were based on a measurement survey. | Age, race | 1993–1995 | 0.94(0.76,1.16) | 7 |
12 | Davis S(2002),USA[23] | 813 cases were identified by the Cancer Surveillance System of the Fred Hutchinson Cancer Research Center. | 793 controls were resident and identified by random digit dialing. | Measurements in the home and self-reported measures of at-home electric appliance use. | Race, age and region | November 1992–March 1995 | 0.99(0.77,1.28) | 7 |
13 | Kabat GC (2003a) [22],USA | 1323 cases were identified from Health Care Financing Administration files was from the Long Island Breast Cancer Study Project (LIBCSP) | 1362 controls were from the LIBCSP and controls were residents identified by random digit dialing and Health Care Financing Administration (HCFA) rosters. | Electric blanket use | Age, region | August 1, 1996 to July 31, 1997. | 1.11(0.94,1.30) | 6 |
14 | Kabat GC(2003b) [22],USA | 666 cases was from the Electromagnetic Fields and Breast Cancer on Long Island Study (EBCLIS*) | I 557 controls were from EBCLIS | Electric blanket use | Age, region, long-term residents | August 1, 1996 to July 31, 1997. | 0.97(0.76,1.23) | 5 |
15 | Schoenfeld ER (2003) [16], USA | 576 cases was from the EBCLIS | 585 controls were from EBCLIS | In-home EMF measurements, wire mapping of overhead power lines | Age, region, long-term residents | August 1, 1996, to June 20, 1997. | 1.03(0.82,1.30) | 7 |
16 | Kliukiene J (2003) [17],Norway | 99 breast cancer cases from a cohort of Norwegian female radio and telegraph operators. | 396 controls from the cohort alive at time of diagnosis. | Calculated based on employment information. Magnetic field measurements | Age, region | January 1961 to the end of May 2002. | 1.46(0.78,2.70) | 6 |
17 | Labreche F(2003)[19], Canada | 608 cases were identified from records of pathology departments and cancer registries from hospitals. | 667 controls had 32 different types of cancer from the same hospitals. | Job | Age, same hospital | 1996–1997 | 1.22(0.93,1.61) | 5 |
18 | London SJ (2003) [24], USA | 347 cases were identified by linkage to county and state tumor registries in Los Angeles County, California. | 286 Controls were selected from a random sample of cohort members without breast cancer at baseline. | Exposure was assessed by means of wiring configuration coding | Race, age and region | 1993–1999 | 1.26(0.87,1.83) | 8 |
19 | Zhu K, 2003(2003) [3], USA | 304 cases lived in one of three Tennessee counties were identified through the Tennessee Cancer Reporting System. | 305 controls were selected through random digit dialing. | Electric blanket use | Race, age and county | 1995–1998 | 1.49(0.99,2.23) | 6 |
20 | Kliukiene J (2004) [17],Norway. | 1830 cases of breast cancer were identified in a cohort of women living near a high-voltage power line in Norway. | The 3658 controls were selected randomly from the cohort. | Residential exposure by the lines, occupational exposure by job title, Magnetic field measurements for estimated time weighted average; | Age, region | 1986–1996 | 1.53(1.28,2.85) | 9 |
21 | Forssen (2000) UM[25], Sweden | 440 cases living within 300 meters of transmission lines in the cohort were identified from the Swedish Cancer Registry. | 439,One matched control per case at random was selected. | Residential exposure by the power lines, and occupational exposure by job title, | Age, region, type of house, power line | 1960–1985 | 1.02(0.78,1.35) | 8 |
22 | Forssen UM(2005), Sweden | 18365 cases were identified from the cancer registry gainfully | 101973 controls were selected randomly from the study base. | Job-exposure matrix based on personal magnetic field measurements | Rgion | 1976–1999 | 1.04(0.99,1.08) | 6 |
23 | McElroy JA (2007) [20],USA | 6213 cases were identified through the North Carolina Central Cancer Registry. | 7390 Controls were sampled from lists of the Division of Motor Vehicles and rosters of Medicare beneficiaries. | Job title | Age, region | 1970–2002 | 1.06(0.99,1.14) | 6 |
*:Women eligible for EBCLIS were those LIBCSP participants who had lived in their current residences for 15 years or more (long-term residents).