Serum IgG1, IgG2, and IgG3 antibodies to C. albicans cell wall antigens in patients with systemic candidiasis and controls (group I and II). Antibody levels were analyzed by enzyme-linked immunosorbent assay (<2 log; no detectable antibody activity in serum diluted 1:100). The numbers <7, 7 to 13, and ≥14 indicate less than 7 days, between 7 and 13 days, and 14 days or more, respectively, after the presumed onset of infection (cultivation of Candida from the blood). Symbols: *, P < 0.05; **, P < 0.01; ***, P < 0.001).