TABLE 4.

Sensitivity, specificity, and predictive values for combined detection of IgG1 anti-CW and IgG2 anti-PPM antibodies in patients with systemic candidiasis at different time points after culture-proven candidiasis

Parametera	Combination of IgG1 anti-CW and IgG2 anti-PPMb
	<7 days	7-13 days	>14 days
Sensitivity	70	93	85
Specificity	100	100	100
Positive predictive value	100	100	100
Negative predictive value	86	95	90

^aThe results were calculated per serum sample from patients with systemic candidiasis (one sample) (see footnote b) within the time points indicated and 19 serum samples from controls.

^bIn order to be positive, the individual titers of the two antibodies had to be ≥3 logs, or the combined titers had to be ≥5 logs.