Figure 4. Number of vinclozolin induced transgenerational DMR detected in F3 generation E13 and E16 germ cells, using two different bioinformatic analyses.
(A) The analysis is performed by averaging data from three comparative MeDIP-Chip per developmental time using a statistical cut-off of p<10−4. (B) The analysis is performed by selecting only the DMR that repeatedly appeared as significantly changed in all MeDIP-Chip comparisons (intersection) using a cut-off of p<10−4. (C) A graphical representation of the DMR location in all chromosomes in the rat that were obtained through the intersection analysis for both E13 and E16 germ cell DMR.