Figure 6. Known relationships between genes having DMR in their promoter regions (grey nodes) and differentially expressed genes (red nodes) in control- compared to vinclozolin lineage F3 generation germ cells from: (A) E13 and (B) E16.

Gene node shape code: oval and circle – protein; diamond – ligand; circle/oval on tripod platform – transcription factor; ice cream cone – receptor. Grey connecters represent general regulation, blue – expression regulation, purple – binding, green – promoter binding. Network was derived using Pathway Studio™ software.