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A: Correlation between NPH insulin dose per kilogram per day and serum-induced IR-A and IR-B activation at 36 weeks of insulin therapy. NPH dose per kilogram per day was positively related to IR-A activation. B: Correlation between concentrations of metabolite M1 and serum-induced IR-A and IR-B activation at 36 weeks of GLA therapy. M1 concentrations were positively correlated to IR-A activation.
