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. 2013 Jun 14;62(7):2195–2203. doi: 10.2337/db12-1449

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© 2013 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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FIG. 1. — Serum lipids change in Clock^Δ19 mice. Diurnal profiles of cholesterol (A), TGs (B), FFAs (C), and glycerol (D) in the serum of wild-type (WT; closed circles) and Clock^Δ19 (open circles) mice in DD (n = 3/time point). Time points indicate hours spent in DD after the last lights off. Diurnal profiles of FFAs (E) and glycerol (F) in the serum of wild-type (closed circles) and Clock^Δ19 (open circles) mice in LD conditions (n = 3–5/time point). Time-of-day dependent variations in serum FFA and glycerol levels in WT (black bars) and Bmal1^−/− (white bars) animals kept in DD (n = 3–5/time point). All data are shown as means ± SEM. *P < 0.05; **P < 0.01; ***P < 0.001 by two-way ANOVA with Bonferroni posttest.