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. 2013 Jun 14;62(7):2249–2258. doi: 10.2337/db12-1146

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© 2013 by the American Diabetes Association.

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FIG. 3. — Average energy intake per week and plasma leptin levels from NT and hGLUT4 TG mice fed CD or HFD (n = 5–8 per group). A: Energy intake (kilocalorie equivalent of diet) was averaged over the 8-week feeding period. *Significant difference between diets. Differences between strains are shown. B: Fasting plasma leptin level was measured after 0, 4, and 8 weeks on diet. A strain-specific significant difference is indicated. *Significant difference between 4 and 0 weeks within a strain and diet, and #significant difference between 8 and 4 weeks within a strain and diet. Data were analyzed by one-way ANOVA. UCP-1 (C) and UCP-2 (D) mRNA were measured using qPCR and normalized to TBP mRNA (n = 4 mice per group). *Significant difference by one-way ANOVA.