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The ghrelin signaling pathway in WT and CPT1C KO mice. Hypothalamic protein levels of pAMPK (A and C) and pACC (B and C), MBH mRNA levels of UCP2 measured by real-time PCR (D), and the hypothalamic protein levels of FoxO1 (E and G) and pCREB (F and G) in WT and CPT1C KO mice after 2 h of ICV injection of vehicle (white bars) or 5 μg ICV injection of ghrelin (black bars). *P < 0.05, **P < 0.01, ***P < 0.001 vs. WT mice treated with vehicle.
