Figure 1.

Schematic of adult neurogenesis in the DG and OB. Sagittal view of rodent brain (Top left) showing sites of neurogenesis in the SVZ/OB and SGZ/DG. Cells proliferate mainly in the SVZ, migrate along the rostral migratory stream (RMS) to the OB where (Right) they migrate radially and undergo differentiation and integration into OB circuit. Neuron precursors from the SGZ proliferate and migrate a short distance to the DG (left) before differentiation into granule neurons and integration into the DG circuit.