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. 2012 Apr 1;71(7):618–626. doi: 10.1016/j.biopsych.2011.11.030

Figure 6.

Figure 6

Interaction of BE5.2 (C and T) with brain derived neurotrophic factor promoter 4 (BP4) in response to lithium chloride (LiCl), phorbol-12-myristate-13-acetate (PMA), and forskolin in primary cortical cultures. Primary cortical cultures were co-transfected with either BP4 (A, C, D) or BP4-BE5.2(T), BP4-BE5.2(C), or ΔBP4 (B, D, E) with renilla plasmid. Cells were treated with 1 mmol/L LiCl for 72 hours (A, B), 150 nmol/L PMA for 24 hours (C, D), or forskolin for 24 hours (E, F) before harvest for dual luciferase assay. Relative light units were calculated by normalizing luciferase signal to renilla signal. n ≥ 3, **p < .01. DMSO, dimethyl sulfoxide; n.s., not significant.