Fig. 5.
ECG parameters from chest and limb leads measured as RR, PR, QRS, and QTc intervals for WT and Scn5a+/− hearts before and after the addition of flecainide or quinidine. Ten WT and ten Scn5a+/− hearts were used, with 5 of each exposed to each drug. Results from chest leads are denoted by solid symbols; results from limb leads are denoted by open symbols. †T tests comparing WT and Scn5a+/− hearts giving values indicating significance. *T tests comparing values before and after drug in the same hearts giving values indicating significance.