Table 5.
List of studied physicochemical parameters of various reported ocular MEs.
| Authors | Drug | Physicochemical properties (mean ± SD) | ||||
|---|---|---|---|---|---|---|
| pH | Average diameter (nm) | Refractive index | Surface tension (mN/m) |
Viscosity (mPa·s) |
||
| Gasco et al., 1989 [43] |
Timolol maleate | — |
15 | — | — | 24.8 ± 0.7 |
| Haße and Keipert, 1997 [45] | Pilocarpine nitrate | 5.5–6.0 | 25–45 | 1.37–1.38 | 31-32 | 7.0–9.0 |
| Fialho and da Silva-Cunha, 2004 [24] | Dexamethasone | 6.99 ± 0.02 | 50.85 ± 1.24 (n = 6) |
1.38 ± 0.01 | 27.79 ± 0.01 | 40.27 ± 0.98 |
| Lv et al., 2006 [25] | Chloramphenicol |
— |
53–59.5 | — | — | — |
| Chan et al., 2007 [47] | Pilocarpine HCl |
— | <100 | — | 34 ± 1.6 | 167 |