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. 2013 Sep;4(3):264–284. doi: 10.3978/j.issn.2078-6891.2013.037

Table 1. Published papers of phase III randomised single agent fluoropyrimidine-based chemoradiation documenting pCR.

Trial Patient numbers Chemo RT Dose pCR OS
NSABP RO3, Roh 2009 (27) 267 FUFA 45 Gy/25#/33 days 17% 5 year 74%
CA0/ARO/AIO-94 (Sauer 2004) (28) 394 120 hour 5-FU infusion 50.4 Gy/28#/38 days 8% 4 year 74%
Polish study Bujko 2004, Bujko 2006 (29,30) 157 FUFA 50 Gy/25#/33 days 16% 4 year 66%
FFCD 9203 (Gerard 2006) (31) 375 FUFA 45 Gy/25#/33 days 11.4% 5 year 66%
EORTC 22921 (Bosset 2005,2006) (25,32) 505 FUFA 45 Gy/25#/33 days 13.4% 5 year 65%
All 1,698 211/1,698 (12.4%)