Multiple associations and complexes of the coactivator HCF-1 with chromatin modulation components. The multiple interactions or associations of chromatin modulation machinery are shown relative to HCF-1. Refer to the text for appropriate description and references. (Top Panel) The activities of components/complexes are noted (Ac, acetylation; GlcNAc, O-linked N-acetylglucosamine; dme, demethylation; dUB, deubiquination; dAc, deacetylation). (Bottom Panel) HCF-1 chromatin modulation complexes that have been clearly defined or identified in specific contexts are represented. The HCF-1 complex whose components are critical for viral IE gene expression is boxed.