Skip to main content
. 2013 Jul 16;3:2164. doi: 10.1038/srep02164

Table 3. Top fifty promoter loci with differential methylation between obese asthmatics and obese non-asthmatics.

ID Symbol Entrez Gene Name Methylation HpaII angle difference
Hypermethylated loci
NM_000101 CYBA cytochrome b-245, alpha polypeptide −21.66
NM_006961 ZNF19 zinc finger protein 19 −22.11
NM_015470 RAB11FIP5 RAB11 family interacting protein 5 (class I) −22.53
NM_000755 CRAT carnitine O-acetyltransferase −26.18
NM_004064 CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) −28.04
NM_080649 APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 −28.60
NM_004791 ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) −29.08
NM_006743 RBM3 RNA binding motif (RNP1, RRM) protein 3 −29.72
NM_005054 RGPD5 RANBP2-like and GRIP domain containing 5 −31.06
NM_002208 ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen) −33.12
NM_002002 FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) −35.03
NM_019625 ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 −36.66
NM_152740 HIBADH 3-hydroxyisobutyrate dehydrogenase −39.92
NM_006332 IFI30 interferon, gamma-inducible protein 30 −43.98
NM_183240 TMEM37 transmembrane protein 37 −44.07
NM_001805 CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon −44.37
NM_005037 PPARG peroxisome proliferator-activated receptor gamma −44.94
NM_002774 KLK6 kallikrein-related peptidase 6 −45.46
NM_003486 SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), −47.79
NM_033023 PDGFA platelet-derived growth factor alpha polypeptide −48.40
NM_024552 CERS4 ceramide synthase 4 −48.55
NM_004104 FASN fatty acid synthase −49.08
NM_006793 PRDX3 peroxiredoxin 3 −51.71
NM_172364 CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 −57.17
NM_004472 FOXD1 forkhead box D1 −61.60
Hypomethylated loci
NM_003513 HIST1H2AB/HIST1H2AE histone cluster 1, H2ae 24.78
NM_080816 SIRPG signal-regulatory protein gamma 26.70
NM_001374 DNASE1L2 deoxyribonuclease I-like 2 26.96
NR_023391 CYP4F30P cytochrome P450, family 4, subfamily F, polypeptide 30, pseudogene 29.46
NM_005003 NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 30.03
NM_005265 GGT1 gamma-glutamyltransferase 1 30.76
NM_002718 PPP2R3A protein phosphatase 2, regulatory subunit B″, alpha 31.16
NM_020686 ABAT 4-aminobutyrate aminotransferase 31.99
NM_002066 GML glycosylphosphatidylinositol anchored molecule like protein 35.78
NM_001444 FABP5 fatty acid binding protein 5 (psoriasis-associated) 35.79
NM_181524 PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 36.31
NM_002745 MAPK1 mitogen-activated protein kinase 1 36.33
NM_005855 RAMP1 receptor (G protein-coupled) activity modifying protein 1 39.95
NM_012461 TINF2 TERF1 (TRF1)-interacting nuclear factor 2 42.13
NM_005037 PPARG peroxisome proliferator-activated receptor gamma 44.94
NM_000498 CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 45
NM_178011 LRRTM3 leucine rich repeat transmembrane neuronal 3 45.43
NM_005063 SCD stearoyl-CoA desaturase (delta-9-desaturase) 47.58
NM_007161 LST1 leukocyte specific transcript 1 48.37
NM_004566 PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 52.96
NR_026790 HCG11 HLA complex group 11 53.02
NM_013361 ZNF223 zinc finger protein 223 55.25
NM_173821 CXXC11 CXXC finger protein 11 55.43
NM_006099 PIAS3 protein inhibitor of activated STAT, 3 55.46
NM_017693 BIVM basic, immunoglobulin-like variable motif containing 56.67
NM_015320 ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 71.73