Skip to main content
. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Dev Biol. 2013 Apr 19;379(1):64–75. doi: 10.1016/j.ydbio.2013.04.008

Figure 7. MODEL of pathways induced by dMyc in the FB.

Figure 7

Expression of dMyc in FB favors the secretion of humoral factors responsible for the release of DILP2 from the brain. We have identified potential pathways that are induced by dMyc in the FB. dMyc increases the expression of Fatty Acid Synthase (FAS), Acetyl CoA (ACC) and of Desat1, responsible for the synthesis and modification of fatty acids. Hexokinases (HK-A and C) and Pyruvate Kinases (PyK), glycolytic enzymes, and of Glucose Transporter-1 (Glut-1). Glutamate Synthase (GS1) and Glutaminase, key enzymes in the synthesis of glutamine and glutaminolysis. Evidence also indicates that dMyc increases the expression of SLC38-11 and SLC1A5 amino acid/glutamine transporters suggesting a role in controlling glutamine flux in the FB.