Skip to main content
. Author manuscript; available in PMC: 2013 Jul 16.
Published in final edited form as: JAMA. 2010 Jan 6;303(1):47–53. doi: 10.1001/jama.2009.1943

Table 2.

Sample Size, Dropout Rates, and Baseline Depression Severity in Six Studies that Compared Active Antidepressant Medications to Pill-Placebo

Study N Dropouts
Baseline HRSD Severity
N % Mean SD
Barrett et al. (2001)c
 Placebo 39 8 21 14.38 3.98
 Medication 38 13 34 14.05 2.86
Elkin et al. (1989)c
 Placebo 62 17 27 19.47 4.60
 Medication 57 13 23 19.51 4.62
DeRubeis el al. (2005)b
 Placebo 60 9 15 23.47 2.73
 Medication 120 13 11 23.22 2.70
Dimidjian et al. (2006)b
 Placebo 45 4 9 20.76 4.59
 Medication 82 15 18 20.73 3.94
Philipp et al. (1999)a
 Placebo 46 3 7 22.20 4.15
 Medication 105 3 3 22.70 4.03
Wichers et al. (2009)b,c
Placebo 32 5 16 23.72 2.81
Medication 32 9 28 24.38 3.84

Note. Studies with the same superscript do not differ with respect to mean rates of attrition at p < .05.