Figure 2. p73β expression reduces cell invasive capacity.

The invasive ability of p73α- and p73β-expressing HeLa cells as compared to control pcDNA3 transfected HeLa cells were determined in real-time during 42 h, using Matrigel-coated transwell chamber and the xCELLigence RTCA DP analyzer. Cell Index represents the degree of cell invasion into the reconstituted basement membrane matrix Matrigel. Data shows representative invasion curves for each condition performed in triplicate +SD, out of three independent experiments. At 24 hours, statistical analysis of p73α versus p73β indicates a p-value * <0.05.