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. 2013 Feb 28;4(2):346–361. doi: 10.18632/oncotarget.868

Figure 2. MSC-delivered miR-124 mimic downregulates the expression of SCP-1 in glioma cells.

Figure 2

U87 cells were transfected with either a control miR (Con-miR) or a miR-124 mimic and the expression of SCP-1 was examined using qRT-PCR (A) or Western blot analysis (B) after 3 days. U87 cells were transfected with a SCP-1 3’-UTR-luciferase plasmid followed by transfection with Con-miR or miR-124 mimic. In parallel, U87 cells expressing this plasmid were co-cultured with BM- MSCs or AD-MSCs that were transfected with either a con-miR or miR-124 mimic (C). The luciferase activity of the cells was determined after 72 h of transfection or co-culture (C). The results are the means ± SE of three different experiments. *p < 0.001.